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Russ Johnson

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Russsell C. Johnson, PhD

Russsell C. Johnson, PhD.
Professor Emeritus
University of Minnesota Medical School

Dr. Johnson’s main research interest is molecular pathogenesis, with his primary scientific interest in Borrelia burgdorferi, Lyme disease, virology, immunology and spirochaetaceae. His Borrelia burgdorferi research includes elements of internal medicine, microbiology and spondyloarthropathy. He also studied the agent of human granulocytic ehrlichiosis.

His Lyme disease research is multidisciplinary, incorporating elements of Ixodidae, tick, pathology, skin biopsy, serology, Lyme Arthritis, and thermal denaturation. He explores the relationship between Borrelia burgdorferi and topics such as internal medicine, which overlap with antibody and allergy. The concepts of his microbiology studies are interwoven with issues in titer and molecular biology. His Borrelia research integrates issues of restriction enzyme, thermal denaturation, DNAt, and spleen, His work brings together such families of science as erythema migrans, serology, surgery, and erythema chronicum migrans. He interconnects internal medicine, bacterial vaccines, and Peromyscus. His studies incorporate diverse disciplines such as treponema, strain, and virulence in addition to microbiology. His more recent lab investigation included the study of the ecology of Lyme disease and human granulocytic ehrlichiosis in Minnesota.

His research in Virology is multidisciplinary, relying on both nymph and direct fluorescent, and intersects with topics in antibody, ehrlichiosis, and antigen.

His research on Microbiology also deals with topics like: plasmids, which have a strong connection to molecular biology and clone; and gel electrophoresis which connect with virulence. His studies in Lyme disease integrate themes in fields like amoxicillin, surgery, doxycycline, erythema migrans and erythema chronicum migrans. Russell C. Johnson is interested in tick, which is a branch of virology. As part of his studies on Spirochaetaceae, Russell C. Johnson often connects relevant areas like Borrelia.

Selected Publications:

Borrelia burgdorferi sp. nov.: Etiologic Agent of Lyme Disease, (920 Citations) R. C. Johnson; George P. Schmid; Fred W. Hyde; A. G. Steigerwalt. International Journal of Systematic and Evolutionary Microbiology (1984)

Differentiation of Pathogenic and Saprophytic Leptospires: Growth at Low Temperatures (859 Citations) R. C. Johnson; V. G. Harris. Journal of Bacteriology (1967)

Cross-Reactivity in Serological Tests for Lyme Disease and Other Spirochetal Infections (683 Citations) L. A. Magnarelli; J. F. Anderson; R. C. Johnson. The Journal of Infectious Diseases (1987)

Azithromycin Compared with Amoxicillin in the Treatment of Erythema Migrans: A Double-Blind, Randomized, Controlled Trial (428 Citations) B. J. Luft; R. J. Dattwyler; R. C. Johnson; S. W. Luger. Annals of Internal Medicine (1996)

Immunodiagnosis of human granulocytic ehrlichiosis using culture derived human isolates. Ravyn, M.D., J.L. Goodman, C.B. Kodner, D.K. Westad, L.A. Coleman, S.M. Engstron, C.N. Nelson, and R.C. Johnson. J. Clin. Microbiol. 36:1480-1488 (1998)

Characterization of monoclonal antibodies to an immunodominant protein of the etiologic agent of human granulocytic ehrlichiosis. Ravyn, M.D., L. Lamb, R. Jemmerson, J.L. Goodman, and R.C. Johnson. (1999) Amer. J. Trop. Med. Hyg. 61:171-176

Involvement of birds in the epidemiology of the Lyme disease agent Borrelia burgdorferi. (266 Citations) J. F. Anderson; R. C. Johnson; L. A .Magnarelli; F W Hyde. Infection and Immunity (1986)

Coexistence of antibodies to tick-borne pathogens of babesiosis, ehrlichiosis, and Lyme borreliosis in human sera. (260 Citations) L.A. Magnarelli; J. S. Dumler; J. F. Anderson; R. C. Johnson. Journal of Clinical Microbiology (1995)

Cultivation of Borrelia burgdorferi from erythema migrans lesions and perilesional skin.
(234 Citations) B. W. Berger; R. C. Johnson; C Kodner; L Coleman. Journal of Clinical Microbiology (1992)
Treatment of early Lyme disease (230 Citations) E. M. Massarotti; Steven W. Luger; D. W. Rahn; R. P. Messner. The American Journal of Medicine (1992)

Molecular detection of persistent Borrelia burgdorferi in the urine of patients with active Lyme disease. (217 Citations) J. L. Goodman; P. Jurkovich; J. M. Kramber; R. C. Johnson. Infection and Immunity (1991)

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete. (186 Citations) R. C. Johnson; C. Kodner; M. Russell. Infection and Immunity (1986)
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